Swine Flu (or more correct, H1N1 flu) is now spread all over the world, declared a pandemic by the World Health Organization. It has been reported from countries all over the world, with people contracting the disease, and a majority of them recovering; for a small fraction of them, the disease worsens to the point that the afflicted person dies. One of the major factors that has helped prevent a higher number of deaths is the fact that the virus has not mutated into a virulent form. Currently, the virus is treated by the drug called oseltamivir or Tamiflu. However, like many other diseases, there will be a form of the virus that is resistant to this drug, and because they are more difficult to treat, this strain of the virus spreads.
Scientists are worried about a strain of the virus spreading that is resistant to the drug, and hence are tracking these cases. As an example, there are many forms of other bacteria caused diseases such as TB that have multi-drug resistant strains and which are of major concern to medical personnel the world over (link to article):